Code: 0710-0670
Seraseq® ctDNA Complete™ Reference Material AF2.5%. 25 variants/16 genes in plasma-like matrix. Full-process ctDNA NGS quality control standard.
Price on Application
The Seraseq® ctDNA Complete™ Reference Material (AF2.5%) is a plasma-like, full-process reference standard for NGS-based liquid biopsy ctDNA assays. It contains 25 unique variants across 16 genes — covering 12 SNVs, 7 INDELs, 3 CNVs, and 3 structural variants (SVs) — at AF2.5%, in a synthetic plasma-like matrix enabling end-to-end assay validation including the pre-analytical extraction step.
Quantitated by digital PCR and orthogonally validated with NGS, this material serves as a traceable ground-truth reference for validating the complete liquid biopsy ctDNA workflow.
Key features:
- 25 variants across 16 genes: SNVs, INDELs, CNVs, and SVs in a single sample
- Plasma-like matrix — challenges the full workflow including ctDNA extraction
- Digital PCR-quantitated against GM24385 background
- Orthogonally validated with NGS
- Available at six allele frequencies: WT, 0.1%, 0.5%, 1%, 2.5%, 5%