Seraseq® 22q11 Microdeletion Male Matched Reference Material. Patient-derived cfDNA NIPT reference for 22q11 DiGeorge Syndrome microdeletion NGS assay validatio
The Seraseq® 22q11 Microdeletion Male Matched Reference Material is a patient-derived, SNP-matched maternal-fetal cfDNA reference material for NIPT assay development, validation, and routine run quality control. It simulates a 22q11 Microdeletion pregnancy (DiGeorge Syndrome), providing patient-like commutability across all major NIPT platforms.
Derived from IRB-approved clinical samples through an exclusive collaboration with Stanford Medicine, these matched reference materials contain real maternal and fetal cfDNA — providing superior commutability versus synthetic materials across SNP-based, whole-genome, and targeted NIPT methods.
Key features:
- Patient-derived, SNP-matched maternal-fetal cfDNA for true commutability
- Compatible with all NGS-based NIPT platforms including SNP-based methods
- Plasma-like format — processed identically to clinical cfDNA samples
- Supports NIPT assay validation, QC, and staff competency programmes
- IRB-approved clinical sample sourcing