Seraseq® Trisomy 18 Male Matched Reference Material. Patient-derived SNP-matched cfDNA NIPT reference for T18 (Edwards Syndrome) NGS assay validation and QC.
The Seraseq® Trisomy 18 Male Matched Reference Material is a patient-derived, SNP-matched maternal-fetal cfDNA reference material for NIPT assay development, validation, and routine run quality control. It simulates a Trisomy 18 (T18) pregnancy (Edwards Syndrome), providing patient-like commutability across all major NIPT platforms.
Derived from IRB-approved clinical samples through an exclusive collaboration with Stanford Medicine, these matched reference materials contain real maternal and fetal cfDNA — providing superior commutability versus synthetic materials across SNP-based, whole-genome, and targeted NIPT methods.
Key features:
- Patient-derived, SNP-matched maternal-fetal cfDNA for true commutability
- Compatible with all NGS-based NIPT platforms including SNP-based methods
- Plasma-like format — processed identically to clinical cfDNA samples
- Supports NIPT assay validation, QC, and staff competency programmes
- IRB-approved clinical sample sourcing