The Covaris ME220 Focused-ultrasonicator delivers reliable mid-throughput DNA/RNA shearing for NGS and other applications. Compact design with Adaptive Focused Acoustics (AFA) technology.
The Covaris ME220 Focused-ultrasonicator is a multi-application, mid-throughput benchtop instrument designed for precise, reproducible sample preparation with Adaptive Focused Acoustics (AFA) technology. It enables consistent, isothermal processing for DNA/RNA shearing, chromatin shearing, FFPE extraction, and a wide range of molecular biology applications. With a compact footprint and intuitive operation, it fits seamlessly into any lab.
Features
- Isothermal process: No heat-induced bias; high sample recovery
- Small, compact footprint: Fits easily on any benchtop
- Non-contact, closed vessel: Eliminates cross-contamination and aerosols
- Flexible sample volumes: 15 μl to 1 ml, processing 1 to 8 samples per batch
- Highly reproducible results: Minimal post-process QC required
- Automatable: Compatible with liquid handling robots and 2D barcoded consumables
- Quiet operation: Operates beyond the audible range for comfort
- NIST-traceable calibration: Assures accuracy and reliability
Benefits
- No thermal or mechanical damage: preserves nucleic acid integrity
- Consistent and transferable protocols for variable sample types
- Traceable sample identification
- Easy to implement into existing genomics workflows
Technical Specifications
| Technology | Adaptive Focused Acoustics (AFA) |
|---|---|
| Throughput | Mid-throughput (1 to 8 samples per batch) |
| Design | Compact benchtop |
| Processing Type | Isothermal, non-contact |
| Sample Volumes | 15 μl to 1 ml |
| Primary Applications | DNA/RNA/Chromatin Shearing, FFPE Extraction, Plasma/cfDNA, Cell and Tissue Lysis |
| Features | Automatable, NIST-traceable, 2D barcoded consumables |
| Catalogue Number | 500506-COV |