The Covaris LE220-plus provides scalable high-throughput DNA/RNA shearing with robust AFA technology, supporting demanding NGS workflows.
The Covaris LE220-plus is an advanced, high-throughput Focused-ultrasonicator engineered for production-scale sample processing and seamless automation. It utilizes powerful Adaptive Focused Acoustics (AFA) technology to deliver precise, isothermal energy, ensuring exceptional reproducibility without thermal damage. Designed for the most demanding applications, the LE220-plus integrates flawlessly into automated workflows, providing robust, walk-away sample preparation for large-scale genomics, epigenomics, and proteomics studies.
Features
- High-power, high-throughput system: Engineered for rapid processing of 96- and 384-well plates.
- Full automation compatibility: Designed for effortless integration with robotic liquid handlers and automated lab systems.
- Advanced AFA technology: Delivers controlled acoustic energy for isothermal, non-contact processing that preserves sample integrity.
- Superior reproducibility: Provides industry-leading consistency across wells, plates, and runs for reliable, high-quality data.
- Closed-vessel processing: Eliminates cross-contamination and aerosolization, ensuring sample safety and purity.
- Broad application support: Optimized for DNA/RNA shearing, chromatin shearing, FFPE nucleic acid extraction, and more.
- 2D barcode compatible: Supports fully automated sample tracking and data management.
Benefits
- Maximizes laboratory throughput and efficiency with true walk-away automation.
- Generates the highest quality analyte for sensitive downstream applications like NGS and mass spectrometry.
- Ensures scalable and standardized protocols for large-scale research and clinical sample processing.
- Reduces manual labor and minimizes the potential for human error, increasing data reliability.
Technical Specifications
| Technology | Adaptive Focused Acoustics (AFA) |
|---|---|
| Throughput | High-throughput (96- and 384-well plate compatible) |
| Design | Automation-ready, high-power unit |
| Processing Type | Isothermal, non-contact |
| Sample Volumes | Optimized for high-throughput automated workflows |
| Primary Applications | High-throughput DNA/RNA Shearing, Chromatin Shearing, FFPE Extraction, Biomarker Extraction, Compound Management |
| Features | Full robotic integration, high power, NIST-traceable, advanced process monitoring |
| Catalogue Number | 500569-COV |