The Covaris LE220 delivers reliable high-throughput ultrasonication with AFA technology for consistent DNA and RNA shearing in NGS workflows.
The Covaris LE220 is a high-throughput, automation-ready Focused-ultrasonicator designed for large-scale sample processing in production environments. It delivers the power of Adaptive Focused Acoustics (AFA) technology for isothermal, non-contact sample preparation, ensuring exceptional consistency and reproducibility. Fully integrable with robotic platforms, the LE220 is the gold standard for demanding, high-throughput applications, including DNA shearing for NGS, chromatin processing, and biomarker extraction.
Features
- High-throughput design: Processes samples in 96- and 384-well plates to maximize productivity.
- Automation-ready: Seamlessly integrates with leading liquid handling robots for complete walk-away operation.
- Isothermal AFA technology: Preserves sample integrity by eliminating heat-induced damage and bias.
- Exceptional reproducibility: Delivers uniform processing across all wells for highly reliable and consistent data.
- Non-contact, closed-vessel system: Prevents cross-contamination and aerosolization, ensuring sample purity.
- Robust and reliable: Built for continuous operation in demanding, high-throughput laboratory settings.
- Broad compatibility: Supports a wide range of sample types and volumes with optimized protocols.
Benefits
- Significantly increases sample processing capacity and workflow efficiency.
- Generates superior quality analyte for the most sensitive downstream analyses.
- Provides standardized and scalable protocols ideal for large-scale research and clinical labs.
- Reduces manual handling, minimizes errors, and ensures maximum process control.
Technical Specifications
| Technology | Adaptive Focused Acoustics (AFA) |
|---|---|
| Throughput | High-throughput (96- and 384-well plate compatible) |
| Design | Automation-ready, integrated unit |
| Processing Type | Isothermal, non-contact |
| Sample Volumes | Optimized for plate-based automated workflows |
| Primary Applications | Automated High-throughput DNA/RNA Shearing, Chromatin Shearing, FFPE Extraction, Compound Management |
| Features | Full robotic integration, NIST-traceable calibration, high-throughput processing |
| Catalogue Number | 500219-COV |