Code: A01052
QuantideX qPCR ESR1 exoMutation Kit detects 11 ESR1 mutations from plasma by qPCR for metastatic breast cancer resistance research.
Price on Application
QuantideX qPCR ESR1 exoMutation Kit is a liquid-biopsy real-time PCR (qPCR) assay that detects 11 ESR1 ligand-binding-domain mutations (E380Q, V422del, S463P, L536H/P/R, Y537S/N/C/D, D538G) from 2 mL of plasma. The assay co-analyzes circulating tumor DNA (ctDNA) and exosomal RNA, achieving sensitivity down to approximately 0.025–0.08% variant allele frequency (VAF), with sample-to-answer results in under 8 hours.
- Diseases Tested: Metastatic Breast Cancer
- Technology: Liquid-biopsy real-time qPCR (ctDNA + exosomal RNA)
- Format: 50 reactions per kit (RUO)
- Sample type: Plasma (2 mL)
- Applications: Monitoring endocrine-therapy resistance in HR-positive metastatic breast cancer research