Tecan IBL International offers a comprehensive range of ELISAs, antibodies, immunoassays and recombinant proteins for research use only.
Interleukin-1 (IL-1) is a critical family of cytokines involved in the regulation of inflammatory responses and immune functions. The family primarily comprises two distinct proteins: IL-1α and IL-1β. Although they differ slightly in structure and processing, they share several key characteristics:
- Molecular Weight: Both IL-1α and IL-1β have similar molecular weights.
- Biological Effects: They exhibit comparable biological activities, including pyrogenicity (fever induction), bone resorption, antigen presentation, and stimulation of both B and T lymphocyte proliferation.
- Receptors: IL-1α and IL-1β utilize the same receptors on target cells, leading to similar downstream signaling pathways.
IL-1 is produced by a variety of cells, including:
- Macrophages and Monocytes: Major sources of IL-1, particularly in inflammatory contexts.
- Adult T Cell Leukemias: Can produce IL-1, influencing disease progression.
- Fibroblasts and Epithelial Cells: Contribute to local inflammation and tissue responses.
- Endothelial Cells and Neutrophils: Participate in immune responses and inflammation.
- Astrocytes: In the central nervous system, they release IL-1 in response to injury or disease.
IL-1 proteins play essential roles in mediating inflammation, regulating immune responses, and influencing various physiological processes.
A separate control set is available upon request for those requiring it for experimental purposes.
This ELISA Kit from Tecan IBL International is for research use only.
Tecan IBL International offers a comprehensive range of ELISAs, immunoassays, antibodies and recombinant proteins.
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